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Da remiziram...vol II.

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Post by Eroo 21/2/2021, 02:39

PS: Dijeljenje cjepiva prema broju stanovnika bi u slučajevima a la DU trebalo promijeniti
     u dijeljenje "prema potrebama".
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Post by Leviathan2 21/2/2021, 02:48

@Eroo wrote:PS: Dijeljenje cjepiva prema broju stanovnika bi u slučajevima a la DU trebalo promijeniti
     u dijeljenje "prema potrebama".
zbog cega ti ne spavas?

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Post by Eroo 21/2/2021, 11:33

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Post by Eroo 21/2/2021, 11:34

@Leviathan2 wrote:
@Eroo wrote:PS: Dijeljenje cjepiva prema broju stanovnika bi u slučajevima a la DU trebalo promijeniti
     u dijeljenje "prema potrebama".
zbog cega ti ne spavas?
Spavam kao mala beba. 8h mi je mjera, a to nikad nije bio moj običaj.
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Post by Eroo 21/2/2021, 11:54

HR: Epidemiološki status danas


14dinci = 4,543 slučaja iliti 111.5/100k stanovnika. 
7dinci = 2,288 slučajeva iliti 56/100k stanovnika. 
Faktor širenja virusa Rt = 1.015 >1!!! 
U županijama koje pridonose ovome se moraju uvesti dodatne mjerer
ili se vratiti na stare.

PS: Malo poslije ćemo vidjeti koliki Rt je naračunao WHO
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Post by Eroo 21/2/2021, 15:12

@Eroo wrote:HR: Epidemiološki status danas


14dinci = 4,543 slučaja iliti 111.5/100k stanovnika. 
7dinci = 2,288 slučajeva iliti 56/100k stanovnika. 
Faktor širenja virusa Rt = 1.015 >1!!! 
U županijama koje pridonose ovome se moraju uvesti dodatne mjerer
ili se vratiti na stare.

PS: Malo poslije ćemo vidjeti koliki Rt je naračunao WHO
Da remiziram...vol II.  - Page 47 5

Razlika je 3.6% što jezanemarljivo.
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Post by Eroo 21/2/2021, 15:31

Srbija:


Što se tiče cijepljenja odlično to rješavaju. 
Mislim da bi im bilo pogrešno zaboraviti da će se virus širiti dok god postoji
milijunski"bazen" za širenje.Na njihovu  žalost o tome odlučuje politika.
Slušam im do nedavno glavnu epidemiologinju Kitić....sad kad je političarka 
govori isto kao Vucić. Ona jedno, a glavni epidemiolog Kon drugo.



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Post by Eroo 21/2/2021, 16:10

Đikić i Lenhard o istraživanju Lauca i Primorca

https://www.index.hr/vijesti/clanak/djikic-i-lenhard-o-istrazivanju-lauca-i-primorca-nema-ni-statistike-ni-logike/2255972.aspx


Obično nadgornjavanje i ništa više od toga. Kritizar možeš ako si sam učinio više i znaš više. 
Đikić ne nudi više od onoga što su od sebe dali Lauc i Primorac. 

Osobno se oslanjam na američka istraživanja o kojima govori njihov CDC. Za procjenu postotka imuniteta polaze od ukupnog broja umrlih.
Rekoše sljedeće (odprilike):
Postotak umrlih u području NY je u odnosu na broj potvrđenih i nepotvrđenih pozitivnih iznosio 0.3%, a u području Floride 0.4%. 
Preporuka CDC: kao dobra procjena(općenito!) je 0.3% ("...ili čak i manje...").



Sam koristiom upravo navedeni postotak, jer bolje nemamo. Za sada. 
Tako, ako imamo  broj umrlih/1 milijun stanovnika, taj broj množimo sa 100 i dijelimo s tri i dobijem mo broj ljudi s imunitetom 
u  jednom milijunu stanovnika. Prva dva broja je upravo postotak postignutog imuniteta populacije.



Problem imamo u situaciji kada je postotak zaraženih (na 100k populacije) u populaciji starijih -iznad 65 i 80 godina- velik.
Taj problem sam imao u slučaju Slovenije, gdje je izrazito velik.

Te podatke možete pronaći ovdje: ecdc

https://covid19-country-overviews.ecdc.europa.eu/
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Post by Eroo 21/2/2021, 19:57

No com. 

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Post by Gnječ 21/2/2021, 20:19

hajde da vas malo razgalim i razveselim u vašoj balkanskoj močvari :D

pa da krenemo:

New SARS-CoV-2 Variant B.1.525 With More Than 20 Mutations Including E484K, 9 Non-Synonymous And 69-70 Spike Deletion Emerges in Britain!
Source: B.1.525 Variant Feb 16, 2021 6 days ago

While the United Kingdom is celebrating its milestone of hitting more than 15 million vaccinations, a new concerning SARS-CoV-2 variant has made its debut in the country with more than 32 cases so far identified and more worrisome is the fact that there could be thousands more as the new variant also yields a S gene dropout in PCR tests, making it more difficult to be picked up by current testing protocols.


The UK can forget about it concerns about the B.1.1.7 variant as this new B.1.525 variant also carries the immune evasive E484K mutation not to mention other worrying new mutations.

The new B.1.525 variant has about 20 mutations, 9 non-synonymous mutations, the 69-70 spike deletion seen in the initial UK B.1.1.7 variant, the nsp6 deletion seen in the B.1.351 variant in South Africa and P.1 variant in Brazil.

It also features the Q677H and F888L mutations and a 144 deletion.

The researchers say the variant has similar characteristics to the Kent variant, B117, and includes the E484K mutation to the spike protein.

The E484K mutation is present in variants that emerged in South African and Brazil and is thought make the virus better able to evade neutralizing antibodies produced by the body.
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Post by Gnječ 21/2/2021, 20:23

As Predicted, First SARS-CoV-2 Reassortant Strain Emerges Involving The Recombination of Two Variants Resulting In A Heavily Mutated Coronavirus
Source: SARS-CoV-2 Reassortant Strains Feb 17, 2021 5 days ago

SARS-CoV-2 Reassortant Strains: Since late 2020, Thailand Medical News has been predicting the emergence of reassortant strains during this COVID-19 pandemic in which the SARS-CoV-2 coronavirus might combine with other coronaviruses or even other viruses to produce a totally new strain with unique characteristics.

Such a reassortant strain has finally emerged in Los Angeles although in this case, it is a little bit disappointing as it involves the recombination of two unique SARS-CoV-2 variants ie the UK variant B.1.1.7 recombining with the Californian variant known as B.1.429 resulting in an extremely potent heavily mutated coronavirus.

In this instance, the UK and California variants of the SARS-CoV-2 coronavirus appear to have combined into a heavily mutated hybrid, sparking concern that we may be entering a new phase of the COVID-19 pandemic

The two of concern variants of the SARS-CoV-2 coronavirus, each already with numerous unique mutations have combined their genomes to form a heavily mutated hybrid version of the virus.

This “recombination” event was discovered in a virus sample in California, provoking warnings and concerns that more potent SARS-CoV-2 coronavirus strains with unknown characteristics are heralding new phase of the pandemic.

This new hybrid virus is the result of recombination of the highly transmissible B.1.1.7 variant discovered in the UK and the B.1.429 variant that originated in California and which may be responsible for a recent wave of cases in Los Angeles because it carries a mutation making it resistant to some antibodies.

This new reassortant strain was discovered by Dr Bette Korber at the Los Alamos National Laboratory in New Mexico, who told a meeting organized by the New York Academy of Sciences that she had seen “pretty clear” evidence of it in her database of US viral genomes.

This recombinant strain would be the first to be detected in this pandemic. In December and January, two research groups independently reported that they hadn’t seen any evidence of recombination, even though it has long been expected as it is common in coronaviruses.
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Post by Gnječ 21/2/2021, 20:26

Just As The World Is Beginning To Deal With SARS-CoV-2 Variants, Fatal H5N8 Avian Flu Cases In Humans Debuts In Russia!
Source: H5N8 Avian Flu Feb 21, 2021 18 hours ago

Just as the world is beginning to deal with the threat of emerging SARS-CoV-2 variants globally, Russia announced on Saturday that its scientists had detected the first cases of transmission of the H5N8 strain of avian flu to humans and had alerted the World Health Organization.

Russian health authorities had discovered the first human cases of the highly infectious H5N8 bird flu virus at a poultry farm in the south of the country; it emerged a few days ago.

Russian scientists identified seven workers who were infected with the virus in December. It is the first time this strain of avian influenza which is deadly to birds has been identified in humans.

The head of Russia's health watchdog Rospotrebnadzor, Dr Anna Popova in a televised interview, said scientists at the Vektor laboratory had isolated the strain's genetic material from seven workers at a poultry farm in southern Russia, where an outbreak was recorded among the birds in December.

She added, "Information about the world's first case of transmission of the avian flu (H5N8) to humans has already been sent to the World Health Organization.”

The deadly H5N8 strain of bird flu was detected in poultry in the UK in December 2020 according to the European Food Safety Authority. Hundreds of thousands of birds including turkeys were slaughtered in a bid to stall the spread of the virus.

Alarmingly the highly infectious disease which has an avian mortality rate up to 100 per cent has also been detected in migratory and wild birds across the continent.

The H5N8 strain of bird flu has never before been previously reported to have spread to humans.

Dr Popova praised "the important scientific discovery," saying "time will tell" if the virus can further mutate.
She stressed, "The discovery of these mutations when the virus has not still acquired an ability to transmit from human to human gives us all, the entire world, time to prepare for possible mutations and react in an adequate and timely fashion.”

Humans can get infected with avian and swine influenza viruses, such as bird flu subtypes A(H5N1) and A(H7N9) and swine flu subtypes such as A(H1N1).

It was said that according to the WHO, (An organization that is famous for getting things wrong!) people usually get infected through direct contact with animals or contaminated environments, and there is no sustained transmission among humans.(Similarly to what they had said initially in the case of the SARS-CoV-2 coronavirus!)

The H5N1 flu in people can cause severe disease and has a 60 percent mortality rate.
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Post by Gnječ 21/2/2021, 20:28

Japan Identifies Another Alarming Variant With E484K Mutation That Likely Originated From South-East Asia, Turkey, France, India Also Sees New Variants
Source: SARS-CoV-2 Variants Feb 20, 2021 1 day ago

Japanese Authorities have identified another alarming SARS-CoV-2 variant that bears the immune evasive mutation E484K. Japanese health authorities have confirmed the identification of the new variant of SARS-CoV-2 coronavirus also said that an infection cluster involving this new variant has emerged at a Tokyo immigration facility, presenting new challenges as the country tries to overcome a third wave of the pandemic.

The Japanese government is raising surveillance against mutant varieties as they may be more resistant to vaccines, which Japan started to distribute this week.

Kato added, “It may be more contagious than conventional strains, and if it continues to spread domestically, it could lead to a rapid rise in cases.”

There are speculations that the new variant likely originated from a South-East Asian country with a reputation of falsely boasting about its so called efficiency in controlling the COVID-19 crisis in its own country despite lack of mass testing, strict laws of divulgence on any data about the status of SARS-CoV-2 infections in its country along with lack of frequent genomic sequencings of all new cases. The country is also famous for its citizens coming to work illegally in East Asian countries as masseuses or as prostitutes.

Japanese experts confirmed that the new variant is different from other types that have been found sporadically in Japan and also different from those found in UK, South Africa or Brazil according to the National Institute of Infectious Diseases. It has the E484K mutation on the spike protein of the virus that has been found in other variants, which may undermine the effectiveness of vaccines.
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Post by Gnječ 21/2/2021, 20:30

Malaysian Researchers Discover that SARS-CoV-2 Infections And Lung Cancer Share Common Pathways And Genes
Source: SARS-CoV-2-Cancer Feb 20, 2021 2 days ago

Malaysian Researchers Dr Suresh Kumar and Dr Kang Soon Nan from the Faculty of Health and Life Sciences, Management and Science University-Malaysia and Dr Kalimuthu Karuppanan from the Division of Cardiovascular Medicine, Radcliffe Department of Medicine, Wellcome Centre for Human Genetics, University of Oxford, Oxford-UK have in a new study discovered that SARS-CoV-2 infections and lung cancer share a common pathway.

To date the detailed molecular mechanism of SARS-CoV-2 infection in lung cancer patients was not discovered yet at the pathway level. This study was about determining the common key genes of COVID-19 disease and lung cancer through network analysis. The hub genes associated with COVID-19 and lung cancer were identified through Protein-Protein interaction analysis. The hub genes are ALB, CXCL8, FGF2, IL6, INS, MMP2, MMP9, PTGS2, STAT3 and VEGFA. Through gene enrichment, it is identified both COVID-19 and lung cancer have a common pathway in EGFR tyrosine kinase inhibitor resistance, IL-17 signaling pathway, AGE-RAGE signaling pathway in diabetic complications, HIF-1 signaling pathway and pathways in cancer.

The study findings have numerous possible implications.

The study findings were published on a preprint server and are currently being peer reviewed. https://www.biorxiv.org/content/10.1101/2021.02.16.431364v1
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Post by Gnječ 21/2/2021, 20:33

British Study Shows That More Than 50 Percent Of Recovered Hospitalized COVID-19 Patients Exhibit Heart Damage!
Source: COVID-19-Heart-Issues Feb 18, 2021 3 days ago

COVID-19-Heart-Issues: A new study by researchers from the University College London, Royal Free London NHS Foundation Trust, Imperial College Healthcare NHS Trust, Barts Heart Centre and the National Heart and Lung Institute-UK has found that more than 50% of patients who have been hospitalized with severe COVID-19 and who show raised levels of a protein called troponin have damage to their hearts. The injury was detected by magnetic resonance imaging (MRI) scans at least a month after discharge.

It has been known that troponin elevation is common in hospitalized COVID-19 patients, but underlying aetiologies are ill-defined. The study team used multi-parametric cardiovascular magnetic resonance (CMR) to assess myocardial injury in recovered COVID-19 patients.

For the study, 148 patients (64 ± 12 years, 70% male) with severe COVID-19 infection [all requiring hospital admission, 48 (32%) requiring ventilatory support] and troponin elevation discharged from six hospitals underwent convalescent CMR (including adenosine stress perfusion if indicated) at median 68 days. Left ventricular (LV) function was normal in 89% (ejection fraction 67% ± 11%). Late gadolinium enhancement and/or ischaemia was found in 54% (80/148). This comprised myocarditis-like scar in 26% (39/148), infarction and/or ischaemia in 22% (32/148) and dual pathology in 6% (9/148).

Importantly myocarditis-like injury was limited to three or less myocardial segments in 88% (35/40) of cases with no associated LV dysfunction; of these, 30% had active myocarditis. Myocardial infarction was found in 19% (28/148) and inducible ischaemia in 26% (20/76) of those undergoing stress perfusion (including 7 with both infarction and ischaemia). Of patients with ischaemic injury pattern, 66% (27/41) had no past history of coronary disease. There was no evidence of diffuse fibrosis or oedema in the remote myocardium (T1: COVID-19 patients 1033 ± 41 ms vs. matched controls 1028 ± 35 ms; T2: COVID-19 46 ± 3 ms vs. matched controls 47 ± 3 ms).

The study found that during convalescence after severe COVID-19 infection with troponin elevation, myocarditis-like injury can be encountered, with limited extent and minimal functional consequence. In a proportion of patients, there is evidence of possible ongoing localized inflammation. A quarter of patients had ischaemic heart disease, of which two-thirds had no previous history. Whether these observed findings represent pre-existing clinically silent disease or de novo COVID-19-related changes remain undetermined. Diffuse oedema or fibrosis was not detected.

The study findings were published in the peer reviewed European Heart Journal. https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehab075/6140994
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Post by Gnječ 21/2/2021, 20:37

Be Prepared For Catastrophic Third And Fourth Waves Where Newer SARS-CoV-2 Variants And Reassortant Strains Will Cause Massive Deaths Globally!

Source: COVID-19 Third And Fourth Waves Feb 14, 2021 7 days ago

For those still living in “Lalaland’ and thinking that with the advent of the COVID-19 vaccines, things would go back to normal soon, air travel would would resume, the tourism industry will start to return back to normal and that border closures and lock downs will cease to exists, there is a huge rude shock awaiting them: the COVID-19 pandemic is going to last for a few years, at least for 4 to 6 years according to experts.

Worse is the fact that it is not going to get any better. Rather the coming global third and fourth waves are expected to be far more catastrophic.

The current COVID-19 vaccines as confirmed by authorities now and even by those that were advocating them, does not stop a person from getting infected neither does it stop the spread of the COVID-19 disease. The only thing that it can do as claimed by vaccine manufacturers now is that it can stop individuals from developing severe conditions if they are infected with the virus. (A claim that is hard to verify as already about 50 percent of the people getting infected are asymptomatic while less than 12 percent or the population once infected develop severe conditions.

Most of those that develop COVID-19 severity are often those aged 65 above and also those with underlying medical conditions including diabetes, obesity, cardiovascular issues, cancer etc.

To make things even confusing, in certain countries like Germany and France, vaccines are no longer allowed for the elderly above 65. https://edition.cnn.com/2021/01/28/europe/germany-astrazeneca-vaccine-coronavirus-grm-intl/index.html

https://www.bbc.com/news/world-europe-55901957

Also COVID-19 vaccines are now also not recommended for those with allergies, autoimmune conditions and also other medical conditions.
https://www.cdc.gov/coronavirus/2019-ncov/vaccines/safety/allergic-reaction.html#:~:text=If%20you%20have%20had%20a,not%20get%20the%20second%20dose.

https://www.cdc.gov/coronavirus/2019-ncov/vaccines/recommendations/underlying-conditions.html

So really what the COVID-19 vaccines are for if the vulnerable cannot be protected? To seek answers for that, one has to really ask Dr Anthony Fauci, Bill Gates and the other billionaires and technocrats controlling all the narratives on the COVID-19 vaccines. (note that you are no longer allowed to mention anything negative about the COVID-19 vaccines as Facebook can ban you and so can Twitter and Google etc.)

To some, it is believed that the debut of the vaccines are ways for governments to only to pacify the masses and buy more time to prevent social unrests and a total collapse of the economic stability.

Even more interesting now is the fact that numerous variants has emerged with some even resistant to the effects of the vaccines despite many manipulated and ‘bought’ studies by the manufacturers claiming otherwise.

Also worrying is the fact these new variants are driving reinfections as in the case of the city of Manaus in Brazil. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00183-5/fulltext

What is even more interesting is the fact that those getting reinfected with the new variants are exhibiting more severe conditions.
https://www.jpost.com/health-science/patient-reinfected-with-south-african-covid-variant-in-serious-condition-658907

https://www.reuters.com/article/health-coronavirus-brazil-reinfection/south-african-coronavirus-variant-detected-in-reinfection-case-in-brazil-idUSKBN29D33S

https://www.rfi.fr/en/france/20210214-french-patient-critical-after-reinfection-with-south-african-covid-variant-health-vaccines-astra-zeneca-infection?ref=tw_i

https://www.sciencedirect.com/science/article/pii/S2405844021000566

Now what is even more intriguing is the fact that it is estimated that at least 30 percent of the world population (7.67 billion) could already be affected by the SARS-CoV-2 with more than 50 percent simply asymptomatic and the other majority only experiencing mild symptoms. In many countries there is a shortage of testing or no testing and while in others, governments are deliberately concealing the numbers.

To truly understand what is going to happen in the third wave and fourth wave, one has to go back to the first wave and the ongoing second wave. In this two waves, more people were/are getting infected with the SARS-CoV-2 virus and the numbers can be really astronomical as the virus is literally ‘super’ airborne and can remain infectious for longer periods in the environment. It is also being speculated that the virus is also evolving to withstand harsher environmental conditions outside the host. It is now even suspected of being water borne and also food borne.
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Post by Gnječ 21/2/2021, 20:42

i tako...lijepe vijesti nedjeljom. u rvackom mordoru je silenzio stampa. jedini izvor informacija je Don Anemio i njegova vojska ubojica kriminalaca tipa: Lauc, Bakić, Primorac, onda ona wannabe časna sestra izbosne, onih par harlekina kobasičara iz civilne zaštite...

nek mi ne zamjere svi ostali rvacki kriminalci koje sam zaboravio imenovati :D
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Post by Speare Shaker 21/2/2021, 20:45

@Gnječ wrote:
The E484K mutation is present in variants that emerged in South African and Brazil and is thought make the virus better able to evade neutralizing antibodies produced by the body.

Imunitet se ne postiže samo putem antitijela.

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Post by Gnječ 21/2/2021, 20:48

@Speare Shaker wrote:
@Gnječ wrote:
The E484K mutation is present in variants that emerged in South African and Brazil and is thought make the virus better able to evade neutralizing antibodies produced by the body.

Imunitet se ne postiže samo putem antitijela.


napiši stručni rad na tu temu i neka ti ga objave u Lancet.
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Post by Speare Shaker 21/2/2021, 20:50

@Gnječ wrote:
@Speare Shaker wrote:
@Gnječ wrote:
The E484K mutation is present in variants that emerged in South African and Brazil and is thought make the virus better able to evade neutralizing antibodies produced by the body.

Imunitet se ne postiže samo putem antitijela.


napiši stručni rad na tu temu i neka ti ga objave u Lancet.

Čemu, kad su već neki drugi napisali što je trebalo napisati.

Ogroman broj ljudi je zapravo već imun na koronu? Znanstvenici: ‘Nešto se definitivno događa‘
‘Naša hipoteza je, dakako, da se radi o imunitetu proizašlom iz običnih prehlada koje također uzrokuju koronavirusi‘

Piše: Silvija Novak
Objavljeno: 19. rujan 2020. 13:35

Do sada se činilo da ljudi nemaju otprije postojeći imunitet na virus SARS-CoV-2, no je li to doista tako? Znanstvenici sada istražuju moguće imunološke odgovore, piše British Medical Journal.

Čak i u lokalnim područjima koja su doživjela neke od najvećih porasta prekomjernih smrtnih slučajeva tijekom pandemije covida-19, serološka ispitivanja od vrhunca epidemije pokazuju da tek oko petine ljudi ima antitijela na SARS-CoV-2: 23 posto u New Yorku, 18 posto u Londonu i 11 posto u Madridu. Među općom populacijom brojevi su znatno niži, a mnoga nacionalna istraživanja izvještavaju o jednoznamenkastim brojevima.

S obzirom na to da su odgovori javnog zdravstva širom svijeta temeljeni na pretpostavci da je virus ušao u ljudsku populaciju bez prethodno postojećeg imuniteta prije pandemije, četiri podatka navode na zaključak da virus ima, kao što je rekao Mike Ryan, šef za izvanredne situacije Svjetske zdravstvene organizacije, 'dug put izgaranja'.

No niz studija koje su zabilježile T-stanice koje reagiraju na SARS-CoV-2 i kod ljudi koji nisu bili u doticaju s virusom, sada otvaraju nova pitanja o stvarnoj prirodi epidemije.

Ne tako novi koronavirus?

Najmanje šest studija ukazalo je na postojanje T-stanica reaktivnih na SARS-CoV-2 kod 20 do 50 posto ljudi koji, koliko je poznato, nisu bili u kontaktu s virusom.

U istraživanju krvi od donora čiji su uzorci u SAD-u prikupljani između 2015. i 2018., kod 50 posto su pronađeni oblici T-stanica koje reagiraju na SARS-CoV-2. Slična studija provedena je u Nizozemskoj te su u uzorcima prikupljenima davno prije pandemije pronađene T-stanice kod dvoje od deset ljudi koji nisu bili izloženi virusu.

U Njemačkoj reaktivne T- stanice uočene su kod trećine
na SARS-CoV-2 seronegativnih zdravih darivatelja krvi (23 od 68).
U Singapuru je tim znanstvenika analizirao uzorke uzete od ljudi koji nisu bili u kontaktu sa SARS-om ili covidom-19; 12 od 29 uzoraka uzetih prije srpnja 2019. pokazali su reaktivnost na SARS-CoV-2, baš kao i sedam od 11 ljudi koji su bili seronegativni na virus. Reaktivnost je također uočena u Velikoj Britaniji i Švedskoj.

Iako su ove studije male i još ne pružaju precizan uvid u otprije postojeći imunološki odgovor na SARS-CoV-2, teško ih je zanemariti, a nekoliko ih je objavljeno i u časopisina Cell i Nature.
Alessandro Sette, imunolog s Instituta za imunologiju La Jolla u Kaliforniji i autor nekolicine studija, kaže: 'U ovom trenutku imamo nekoliko studija koje pokazuju reaktivnost na različitim kontinentima. Kao znanstvenik znam da je to nešto što ima čvrste osnove.'

Istraživači su također uvjereni da su na tragu utvrđivanja porijekla tog imunološkog odgovora.

'Naša hipoteza je, dakako, da se radi o imunitetu proizašlom iz običnih prehlada koje također uzrokuju koronavirusi', kaže Daniela Weiskopf, jedna od autorica studije.
'Pokazali smo da je to stvarna imunološka memorija proizašla dijelom iz virusa obične prehlade.'

Znanstvenici u Singapuru došli su do sličnih zaključaka o ulozi virusa obične prehlade, no naznačili su i da reaktivnost T-stanica možda dolazi i od nekih drugih koronavirusa, možda i od onih životinjskih.

Uzevši sve to zajedno, sve veći broj znanstvenih radova koji su dokumentirali otprije postojeći imunološki odgovor na SARS-CoV-2, možda će potaknuti one koji se bave upravljanjem pandemijom da ponovno analiziraju neke temeljne pretpostavke o tome kako mjeriti osjetljivost stanovništva i pratiti doseg širenja pandemije.

Je li imunitet stanovništva podcijenjen?

Istraživanje seroprevalencije, koje detektira prisutnost antitijela, preferirana je metoda mjerenja omjera ljudi u nekoj populaciji koji su bili inficirani virusom SARS-CoV-2 i koji su zbog toga do neke mjere imuni, i procjene pragova imuniteta krda što daje osjećaj o tome u kojoj se fazi pandemije nalazimo.
Bez obzira na to hoćemo li to postići prirodnim putem ili cijepljenjem, čini se da sve skupa neće biti gotovo dok ne postignemo imunitet krda.

Činjenica je da tek manji broj ljudi, čak i u najpogođenijim područjima, ima antitijela na SARS-CoV-2, što je mnoge navelo na pretpostavku da je pandemija još daleko od završetka.
U New Yorku, gdje se pokazalo da samo petina ispitanih ima antitijela, zdravstveni su djelatnici zaključili da 'praćenje, testiranje i traženje kontakata ostaju glavne javnozdravstvene strategije'.

- Koliki god taj prag imuniteta krda bio, još mu se nismo približili, rekao je Ryan iz Svjetske zdravstvene organizacije.

No poznato je da memorija T-stanica ima sposobnost utjecati na ozbiljnost kliničke slike i podložnost budućim infekcijama, a studije T-stanica zabilježile su otprije postojeću reaktivnost na SARS-CoV-2 kod 20 do 50 posto ljudi što daje naslutiti da antitijela nisu potpuna priča.

- Možda smo malo naivni kad koristimo serološka testiranja za utvrđivanje broja ljudi koji su bili izloženi virusu, kazao je imunolog s Instituta Karolinska Marcus Buggert.
- Imunitet je više od toga, dodao je.

 
https://www.jutarnji.hr/life/znanost/ogroman-broj-ljudi-je-zapravo-vec-imun-na-koronu-znanstvenici-nesto-se-definitivno-dogada-15019955


Last edited by Speare Shaker on 21/2/2021, 20:51; edited 1 time in total

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